Diltiazem

Diltiazem is used for treating supraventricular tachycardia, a rhythm disturbance of the heart. It is also used for controlling heart rate response to other rhythm disturbances, specifically, atrial fibrillation and flutter. It may also be used for other conditions as determined by your doctor.

Use Diltiazem as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Diltiazem is usually given as an injection at your doctors office, hospital, or clinic. If you will be using Diltiazem at home, a health care provider will teach you how to use it. Be sure you understand how to use Diltiazem . Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

Do not use Diltiazem if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.

Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.

If you miss a dose of Diltiazem , use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Diltiazem.

Diltiazem is a calcium channel blocker. It works by slowing the electrical conduction in the heart, slowing heart rate, and/or normalizing heart rhythm.

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Store this medicine at room temperature in a tightly-closed container, away from heat and light.

Do NOT use Diltiazem if:

• you are allergic to any ingredient in Diltiazem
• you have sick sinus syndrome or have second- or third-degree heart block and do not have a pacemaker, or very low blood pressure
• you have atrial fibrillation or flutter and a pre-excitation syndrome (extra conduction pathway in the heart), such as Wolff-Parkinson-White syndrome (WPW) or Lown-Ganong-Levine syndrome (LGL)
• you are receiving injectable beta-blockers (eg, metoprolol) or erythromycin

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have heart failure or have had a recent heart attack with lung congestion, heart block, low blood pressure, a very slow heart rate, or abnormal heart rhythm
• if you have kidney or liver disease

• Cimetidine or protease inhibitors (eg, indinavir) because they may increase the actions and side effects of Diltiazem
• Rifampin because it may decrease the effectiveness of Diltiazem
• Amiodarone, cisapride, digoxin, erythromycin, protease inhibitors (eg, indinavir), quinidine, tricyclic antidepressants (eg, desipramine), theophylline, or general anesthetics because toxic effects on the heart may occur
• Benzodiazepines (eg, midazolam), beta-blockers (eg, metoprolol), buspirone, carbamazepine, cilostazol, corticosteroids (eg, prednisone), cyclosporine, HMG-CoA reductase inhibitors (eg, atorvastatin), macrolide immunomodulators (eg, tacrolimus) because the risk of their side effects, some potentially life-threatening, may be increased by Diltiazem