Tamoxifen

Tamoxifen is used for treating breast cancer that has spread to other sites in the body. It is also used along with other medicines to treat other types of breast cancer. It is used in women who are at high risk for breast cancer and in women with DCIS (after surgery and radiation) to decrease the risk of developing breast cancer. It may also be used for other conditions as determined by your doctor.

Use Tamoxifen as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Tamoxifen comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Tamoxifen refilled.

Tamoxifen may be taken by mouth with or without food.

Take Tamoxifen with water or another nonalcoholic liquid.

Swallow this medication whole. Do not break, crush, or chew before swallowing.

Continue to take Tamoxifen even if you feel well. Do not miss any doses. Taking Tamoxifen at the same time each day will help you to remember to take it.

Tamoxifen is an antiestrogen. It works by blocking the effect of estrogen on certain tumors. This may prevent the growth of tumors that are activated by estrogen.

If you miss a dose of Tamoxifen , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Store Tamoxifen between 68 and 77 degrees F (20 and 25 degrees C) in a tightly closed, light-resistant container. Store away from moisture, heat, and light. Do not store in the bathroom. Do not take tablets after the expiration date printed on the label. Keep Tamoxifen out of the reach of children and away from pets.

Do NOT use Tamoxifen if:

• you are allergic to any ingredient in Tamoxifen
• you are using Tamoxifen to reduce your risk of breast cancer and you have a history of blood clots in the lung or leg
• you are using Tamoxifen to reduce your risk of breast cancer and you also take certain anticoagulants (eg, warfarin)
• you are taking anastrozole

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of blood clots in the legs or lungs
• if you have high levels of calcium in your blood, a weakened immune system, or low levels of white blood cells or platelets in your blood
• if you have high cholesterol or lipid levels
• if you have cataracts or other vision problems
• if you are using cytotoxic cancer medicines
• if you are confined to a bed or chair