Avodart (Dutasteride)

Avodart is used for treating symptoms of benign prostatic hyperplasia (BPH) or enlargement of the prostate gland. It also helps to reduce the risk of urinary blockage and the need for prostate surgery. It may also be used along with other medicines (eg, tamsulosin).

Use Avodart as directed by your doctor.

• Avodart may be taken with or without food.
• Swallow Avodart whole. Do not break, crush, or chew before swallowing.
• It may take 3 to 6 months for Avodart to work.

Avodart is a 5 alpha-reductase enzyme inhibitor. It works by lowering levels of a hormone called dihydrotestosterone (DHT), which is a major cause of prostate growth. Lowering DHT leads to shrinkage of the enlarged prostate gland.

If you miss a dose of Avodart , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Store Avodart between 68 and 77 degrees F (20 and 25 degrees C) in a tightly closed, light-resistant container. Store away from moisture, heat, and light. Do not store in the bathroom. Do not take tablets after the expiration date printed on the label. Keep Avodart out of the reach of children and away from pets.

Do not use Avodart if:

• you are allergic to any ingredient in Avodart or other 5 alpha-reductase inhibitors (e.g., finasteride) ;
• you are pregnant or a female of childbearing age.

• Avodart is absorbed through the skin. Women who are or may potentially be pregnant must not handle crushed or broken tablets because it may cause harm to the fetus. If contact is made with leaking capsules, the contact area should be washed immediately with soap and water and a doctor should be consulted.
• Avodart stays in the blood stream for 4 to 6 months after you stop taking it. Do not donate blood for at least 6 months after your last dose of Avodart to prevent exposure through a blood transfusion to a pregnant woman.
• Avodart may decrease your volume of ejaculate. This does not appear to interfere with normal sexual function.
• Avodart can affect a blood test called prostate-specific antigen (PSA) for the screening of prostate cancer. If you have a PSA test done, you should tell your doctor that you are taking Avodart.
• Lab tests may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
• Avodart is not recommended for use in children; safety and effectiveness have not been confirmed.
• Pregnancy and breast-feeding: Avodart can cause harm to the fetus. Do not use Avodart if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately. It is unknown if Avodart is excreted in breast milk. Do not breast-feed while taking Avodart.