Revatio (sildenafil)

Revatio (sildenafil) relaxes muscles and increases blood flow to particular areas of the body.
Revatio may also be used for other purposes not listed in this medication guide.

Revatio is usually taken three times daily, approximately 4 to 6 hours apart. It can be taken with or without food.

Revatio (sildenafil) is a phosphodiesterase inhibitor. It works by relaxing blood vessels in the lungs, which decreases blood pressure.

If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take extra medicine to make up the missed dose.

Store this medication at room temperature and keep it out of the reach of children.

Do not take Revatio if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, and others), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), and isosorbide mononitrate (Imdur, ISMO, Monoket). Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking Revatio with a nitrate medicine can cause a serious decrease in blood pressure, leading to fainting, stroke, or heart attack.
Before taking Revatio, tell your doctor if you are allergic to any drugs, or if you have:

• heart disease or heart rhythm problems;
• a recent history (in the past 6 months) of a heart attack, stroke, or heart rhythm disorder;
• congestive heart failure;
• high or low blood pressure;
• coronary artery disease;
• liver disease;
• kidney disease;
• a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
• a bleeding disorder such as hemophilia;
• a stomach ulcer;
• retinitis pigmentosa (an inherited condition of the eye);
• a physical deformity of the penis (such as Peyronie's disease); or
• if you have been told you should not have sexual intercourse for health reasons.