Simplicef (Cefpodoxime)

Simplicef tablets are indicated for the treatment of skin infections (wounds and abscesses) in dogs caused by susceptible strains of:

• Staphylococcus intermedius;
• Staphylococcus aureus;
• Streptococcus canis (group G, hemolytic);
• Escherichia coli;
• Pasteurella multocida, and Proteus mirabilis.

• The dose range of Simplicef (cefpodoxime proxetil) tablets is 5-10 mg/kg (2.3-4.5 mg/lb) body weight, administered orally, once a day. The dose may be given with or without food. The determination of dosage for any particular patient must take into consideration such factors as the severity and nature of the infection, the susceptibility of the causative organisms, and the integrity of the patient's host-defense mechanisms. Obtain a sample of the pathogenic organism for culture and sensitivity testing prior to beginning antimicrobial therapy. Once results become available, continue with appropriate therapy.

Simplicef is an orally administered, extended spectrum, semi-synthetic cephalosporin antibiotic.

If you miss to give a dose of Simplicef, give it as soon as possible. If it is almost time for your pet to take the next dose, skip the dose and go back to the regular dosing schedule. Do not double the dose to catch up.

Store Simplicef between 39 and 86 degrees F (4 and 30 degrees C). Keep Simplicef out of the reach of children and away from pets.

• Not for human use. Keep this and all drugs out of reach of children. Antimicrobial drugs, including penicillins and cephalosporins, can cause allergic reactions in sensitized individuals.
• To minimize the possibility of allergic reactions, those handling such antimicrobials, including Simplicef, are advised to avoid direct contact of the product with the skin and mucous membranes.